apc gene editing (TaKaRa)

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TaKaRa apc gene editing
Apc Gene Editing, supplied by TaKaRa, used in various techniques. Bioz Stars score: 94/100, based on 3 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/apc+gene+editing/AAVpro+CRISPR%2FCas9+Vector+System/10__7554_slash_elife__82311-177-47-55
Average 94 stars, based on 3 article reviews

apc gene editing - by Bioz Stars, 2026-10

94/100 stars

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Bioprocessing:

Article Title: Intermittent fasting induces rapid hepatocyte proliferation to restore the hepatostat in the mouse liver
Article Snippet: .. For all AAV studies, mice were intraperitoneally injected with 1 × 10 11 genome copies per mouse at 6–8 weeks of age to induce liver-specific depletion of Klb or Tbx3 (AAV8-TTR-Cre, Vector Bio Labs, Malvern, PA), Fgf15 overexpression (AAV8-TTR-FGF15; Addgene deposit 81516), or Apc gene editing (AAV8-U6-sgAPC; derived from Clontech 632609). .. For AAV control studies, an AAV8-Null vector containing no transgene (Vector Bio Labs, Malvern, PA) was used on a combined cohort of Tbx3 flox / flox and Klb flox / flox mice.

Article Title: Intermittent fasting induces rapid hepatocyte proliferation to restore the hepatostat in the mouse liver
Article Snippet: .. For all AAV studies, mice were intraperitoneally injected with 1 × 1011 genome copies per mouse at 6–8 weeks of age to induce liver- specific depletion of Klb or Tbx3 (AAV8- TTR- Cre, Vector Bio Labs, Malvern, PA), Fgf15 overexpression (AAV8- TTR- FGF15; Addgene deposit 81516), or Apc gene editing (AAV8- U6- sgAPC; derived from Clontech 632609). .. For AAV control studies, an AAV8- Null vector containing no transgene (Vector Bio Labs, Malvern, PA) was used on a combined cohort of Tbx3 flox/flox and Klb flox/flox mice.

Injection:

Article Title: Intermittent fasting induces rapid hepatocyte proliferation to restore the hepatostat in the mouse liver
Article Snippet: .. For all AAV studies, mice were intraperitoneally injected with 1 × 1011 genome copies per mouse at 6–8 weeks of age to induce liver- specific depletion of Klb or Tbx3 (AAV8- TTR- Cre, Vector Bio Labs, Malvern, PA), Fgf15 overexpression (AAV8- TTR- FGF15; Addgene deposit 81516), or Apc gene editing (AAV8- U6- sgAPC; derived from Clontech 632609). .. For AAV control studies, an AAV8- Null vector containing no transgene (Vector Bio Labs, Malvern, PA) was used on a combined cohort of Tbx3 flox/flox and Klb flox/flox mice.

Over Expression:

Article Title: Intermittent fasting induces rapid hepatocyte proliferation to restore the hepatostat in the mouse liver
Article Snippet: .. For all AAV studies, mice were intraperitoneally injected with 1 × 1011 genome copies per mouse at 6–8 weeks of age to induce liver- specific depletion of Klb or Tbx3 (AAV8- TTR- Cre, Vector Bio Labs, Malvern, PA), Fgf15 overexpression (AAV8- TTR- FGF15; Addgene deposit 81516), or Apc gene editing (AAV8- U6- sgAPC; derived from Clontech 632609). .. For AAV control studies, an AAV8- Null vector containing no transgene (Vector Bio Labs, Malvern, PA) was used on a combined cohort of Tbx3 flox/flox and Klb flox/flox mice.

Derivative Assay:

Article Title: Intermittent fasting induces rapid hepatocyte proliferation to restore the hepatostat in the mouse liver
Article Snippet: .. For all AAV studies, mice were intraperitoneally injected with 1 × 1011 genome copies per mouse at 6–8 weeks of age to induce liver- specific depletion of Klb or Tbx3 (AAV8- TTR- Cre, Vector Bio Labs, Malvern, PA), Fgf15 overexpression (AAV8- TTR- FGF15; Addgene deposit 81516), or Apc gene editing (AAV8- U6- sgAPC; derived from Clontech 632609). .. For AAV control studies, an AAV8- Null vector containing no transgene (Vector Bio Labs, Malvern, PA) was used on a combined cohort of Tbx3 flox/flox and Klb flox/flox mice.

Review